Orofacial granulomatosis associated with delayed hypersensitivity to cobalt
- 1 September 1990
- journal article
- Published by Oxford University Press (OUP) in Clinical and Experimental Dermatology
- Vol. 15 (5) , 384-386
- https://doi.org/10.1111/j.1365-2230.1990.tb02123.x
Abstract
Orofacial granulomatosis is a distinct clinical and pathological entity characterised by swelling of the lips and lower hall of the face, Ulceration of the oral mucosa may also occur. Granulomas are seen histologically. Orofacial granulomatosis may occur in the Melkerssonn–Rosenthal syndrome, granulomatous cheilitis of Miescher, oral Crohn's disease, sarcoidosis and focal dental sepsis. The increased prevalence of atopy in patients with orofacial granulomatosis and the association with food intolerance suggests the possibility of a role for allergy in at least some cases.Keywords
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