An efficient chemoenzymatic route to the antidepressants (R)-fluoxetine and (R)-tomoxetine

This publication has 23 references indexed in Scilit:

• Lipase-Supported Synthesis of Biologically Active Compounds
  Chemical Reviews, 1995
• A convenient method for preparing enantiomerically pure norfluoxetine, fluoxetine and tomoxetine
  Tetrahedron Letters, 1994
• Some aspects of biocatalysis in organic solvents
  Tetrahedron, 1994
• Enzymes in the synthesis of chiral drugs
  Enzyme and Microbial Technology, 1993
• Practical Asymmetric Synthesis of (R)-Fluoxetine Hydrochloride Catalyzed by (2S, 4S)-4-Dicyclohexylphosphino-2-diphenylphosphinomethyl-1-(N-methylcarbamoyl)pyrrolidine-Rhodium Complex¹
  Synlett, 1991
• Enantioselective and practical syntheses of R- and S-fluoxetines
  Tetrahedron Letters, 1989
• Asymmetric synthesis of both enantiomers of tomoxetine and fluoxetine. Selective reduction of 2,3-epoxycinnamyl alcohol with Red-Al
  The Journal of Organic Chemistry, 1988
• The absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor
  Journal of Medicinal Chemistry, 1988
• Chiral synthesis via organoboranes. 18. Selective reductions. 43. Diisopinocampheylchloroborane as an excellent chiral reducing reagent for the synthesis of halo alcohols of high enantiomeric purity. A highly enantioselective synthesis of both optical isomers of Tomoxetine, Fluoxetine, and Nisoxetine
  The Journal of Organic Chemistry, 1988
• Tomoxetine hydrochloride
  Drugs of the Future, 1986