Host Response to Treponema pallidum Infection
- 1 January 1977
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 55 (1-6) , 476-480
- https://doi.org/10.1159/000231960
Abstract
Levels of phospholipids, glycolipids and cardiolipin were determined in various organs of Treponema pallidum-induced rabbits. The phospholipid levels on the second week of infection decreased significantly in the spleen but remained unchanged in other organs. During the same time, glycolipids decreased significantly in both kidney and heart. 3 days after infection, a brief but significant increase of cardiolipin in the spleen was observed. Heat-killed T. pallidum but not Treponema reiteri caused a similar effect. The possible implication of these changes in the immunopathology of syphilis is discussed.Keywords
This publication has 1 reference indexed in Scilit:
- Two-dimensional chromatography on silica gel-loaded paper for the microanalysis of polar lipidsJournal of Lipid Research, 1966