Phototoxic Potential of Minocycline and Doxycycline
- 1 May 1972
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 105 (5) , 681-683
- https://doi.org/10.1001/archderm.1972.01620080011005
Abstract
In a double-blind study, subjects were exposed to natural sunlight after taking either of two tetracycline antibiotics or placebo capsules for one week. Mild, transient, abnormal sunburn reactions, paresthesias, or both, developed in 11 of 15 subjects who took doxycycline and in none of the subjects who took minocycline or placebo capsules. Tingling and burning of the extremities and other exposed parts was a highly sensitive indicator of abnormal reactions to sunlight.Keywords
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