Estrogenic Inhibition of Growth Hormone-Induced Tibial Epiphyseal Growth in Hypophysectomized Rats
- 1 December 1967
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 81 (6) , 1428-1430
- https://doi.org/10.1210/endo-81-6-1428
Abstract
Previous studies by this group, and by other workers, have suggested that estrogen may antagonize certain peripheral effects of pituitary growth hormone in rats and humans. The present study demonstrates that the partial inhibitory effect of pharmacologic doses of estradiol valerate (3.3-10 [mu]g total dose) on growth hormone-induced widening of the tibial epiphyseal cartilage of hypophysectomized rats occurs independently of the effect of the estrogen on dietary intake in these rats.This publication has 3 references indexed in Scilit:
- Effect of Estrogen Therapy on Carbohydrate Metabolism in AcromegalyJournal of Clinical Endocrinology & Metabolism, 1967
- Human Placental Lactogen: Studies of Its Acute Metabolic Effects and Disposition in Normal Man*Journal of Clinical Investigation, 1967
- BIOASSAY OF HYPOPHYSEAL GROWTH HORMONE: THE TIBIA TEST1Endocrinology, 1949