Low Penetrance, Broad Resistance, and Favorable Outcome of Interleukin 12 Receptor β1 Deficiency
Open Access
- 17 February 2003
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 197 (4) , 527-535
- https://doi.org/10.1084/jem.20021769
Abstract
The clinical phenotype of interleukin 12 receptor β1 chain (IL-12Rβ1) deficiency and the function of human IL-12 in host defense remain largely unknown, due toKeywords
This publication has 61 references indexed in Scilit:
- Inherited Interleukin-12 Deficiency: IL12B Genotype and Clinical Phenotype of 13 Patients from Six KindredsAmerican Journal of Human Genetics, 2002
- Impairment of Mycobacterial But Not Viral Immunity by a Germline Human STAT1 MutationScience, 2001
- Nomenclature for the description of human sequence variationsHuman Genetics, 2001
- Interleukin-12 primes CD4+ T cells for interferon-gamma production and protective immunity during Mycobacterium avium infectionImmunology, 2001
- MYCOBACTERIUM FORTUITUM-CHELONAE COMPLEX INFECTION IN A CHILD WITH COMPLETE INTERLEUKIN-12 RECEPTOR BETA 1 DEFICIENCYThe Pediatric Infectious Disease Journal, 2001
- Impairment of Mycobacterial Immunity in Human Interleukin-12 Receptor DeficiencyScience, 1998
- Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor-Deficient PatientsScience, 1998
- THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune ResponsesAnnual Review of Immunology, 1998
- Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guérin infection and a sibling with clinical tuberculosis.Journal of Clinical Investigation, 1997
- Disseminated Mycobacterium avium infection in a child with decreased tumour necrosis factor productionEuropean Journal of Pediatrics, 1997