The Effects of Androsterone, Oestradiol, and Thyroid Hormone on the Artificial Premature "Climacteric" of Pure Gonadal Origin Produced by Ovariectomy in Rats
This paper is the third in a series reporting the effects of sex and various hormones on the gross and microscopic characteristics of various organs of rats in which an artificial climateric was produced by ovariectomy. The first paper discussed the effects on weights of organs, the second, the effects on the histologic structure of liver and kidneys, and the present article the histologic changes in uterus, vagina, thyroid, and adrenals. Dr. Korenchevsky found that in general the correlative effects of the hormones indicated that their stimulating and possibly anti-aging action on the uterus, vagina, and adrenals produced hypertrophic changes of the normal type. In the case of the thyroid only androgen, of the three hormones used, produced some weak stimulating effect