RENAL FUNCTION AND THE AZOTEMIA FOLLOWING HEMATEMESIS 12

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Abstract
The urea, inulin, and phenol red clearances were detd. in 4 patients with elevated blood urea N content following hematemesis in the absence of shock. In 1, the clearances were normal, while in the other 3, they were reduced possibly as a result of decreased renal blood flow. The reduction, however, was insufficient to account for the increased blood urea content and, moreover, persisted in spite of the return of the blood urea N cone, to normal. To exclude the factor of depression of renal function as a result of toxic products arising from the decomposition of the blood in the intestines, the clearances were detd. in 5 individuals 2 days before and 18 hrs. after the intragastric adm. of 2000 cc. of citrated human blood. Although a distinct rise in the blood urea content occurred, there was no demonstrable change in kidney function at the height of the blood urea N increase.

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