Microbiological Considerations of Polymer Solutions Used in Aqueous Film Coating

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Abstract
Environmental and other pressures are causing pharmaceutical manufacturers to convert earlier developed solvent based film coating procedures to aqueous systems. Factors influencing microbiological proliferation in cellulosic polymer solutions are discussed. Commonly employed water soluble cellulosic polymers have been evaluated for their resistance/susceptibility to microbiological growth. The implications of the findings to the use of such aqueous polymer solutions as pharmaceutical film coatings are discussed

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