ONCE-DAILY ATENOLOL IN HYPERTENSIVE ZIMBABWEAN BLACKS - A DOUBLE-BLIND TRIAL USING 2 DIFFERENT DOSES

  • 1 January 1981
    • journal article
    • research article
    • Vol. 60  (2) , 47-48
Abstract
A double-blind within-patient study was performed on Zimbabwean blacks to investigate the effect of once-daily atenolol on hypertension in doses of 100 and 200 mg/day. Atenolol, 200 mg, produced significant changes in diastolic pressure readings taken in the supine and standing positions and after exercise; with atenolol, 100 mg, modest but non-significant changes occurred. These findings are less impressive than those previously reported in white subjects. Beta-adrenoceptor blocking agents should not be used as drugs of 1st choice for hypertension in the black population.

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