A Device for Continuous Recording of Weight Change Suitable for Physiological Measurements

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Abstract
A strain gauge torsion balance suitable for recording weight changes in organs in vivo is described. The device consists of a beam (5/16 x 30 in. steel rod) suspended at mid-point with a strip of Phosphor bronze (frac12 x 3 x .040 in.). In a balanced condition the beam assumes a horizontal position and the bronze strip is subjected only to vertical forces. When the balanced condition is disturbed, horizontal forces exist which cause the bronze strip to assume a bowed configuration. A pair of strain gauges cemented to the surfaces of the strip allows quantitation of the strains with electrical recording. This device has proved practical in estimating weight changes in the intestine and liver of the dog, in vivo and in the isolated perfused, canine lung, liver and hind leg. Performance characteristics demonstrate stability, sensitivity and linearity adequate for many physiological studies. Submitted on April 2, 1956
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