Chiral Deuteration at C-6 of 1,6-Anhydrohexose Derivatives

Abstract
Photobromination and the succeeding deuteration with tri-n-butyltindeuteride were performed on eight 1,6-anhydro-2,3,4-tri-O-benzoylhexopyranoses to give C-6 chirally deuterated hexopyranoses. The stereochemistry of these two reactions are discussed in terms of steric effects of substituents at C-2, C-3 and C-4 of 1,6-anhydrohexopyranoses.