A practical and efficient method for the construction of the biphenyl framework; nucleophilic aromatic substitution on 2-methoxybenzoates with aryl grignard reagents
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 19,p. 1375-1376
- https://doi.org/10.1039/c39910001375
Abstract
Treatment of 2-methoxybenzoic esters derived from 2, 6-dialkylphenols with aryl Grignard reagents afforded 1,1′-biphenyl-2-carboxylates in excellent yields.Keywords
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