CREATINE PHOSPHOKINASE ACTIVITY IN SERUM OF NEWBORN INFANTS AS AN INDICATOR OF FETAL TRAUMA DURING BIRTH
- 1 December 1966
- journal article
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 38 (6) , 1039-1046
- https://doi.org/10.1542/peds.38.6.1039
Abstract
Serial studies have demonstrated a frequent rise in the activity of the enzyme creatine kinase in the serum of newborn infants following delivery. The rise in activity is independent of the maternal enzyme level. Considerable elevations in serum creatine kinase activity, noted especially at 24 hours of age, have been found in a number of infants delivered as breech presentations, following secondary uterine inertia with oxytocin stimulation, and following emergency Cesarean section after a trial of labor. Muscle damage sustained by the infant during the birth process is suggested as a likely cause for the increase in neonatal serum enzyme activity.Keywords
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