Functional Effect of the C242T Polymorphism in the NAD(P)H Oxidase p22phox Gene on Vascular Superoxide Production in Atherosclerosis
- 10 October 2000
- journal article
- other
- Published by Wolters Kluwer Health in Circulation
- Vol. 102 (15) , 1744-1747
- https://doi.org/10.1161/01.cir.102.15.1744
Abstract
Background—Increased superoxide anion production increases oxidative stress and reduces nitric oxide bioactivity in vascular disease states. NAD(P)H oxidase is an important source of superoxide in ...Keywords
This publication has 3 references indexed in Scilit:
- Relationship of the C242Tp22phox gene polymorphism to angiographic coronary artery disease and endothelial functionAmerican Journal of Medical Genetics, 1999
- Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failureCardiovascular Research, 1999
- The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individualsAtherosclerosis, 1999