OBSERVATIONS ON THE LOCALIZATION OF THE RECEPTOR AREA OF THE BAINBRIDGE REFLEX

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Abstract
Reflexo-genic end-organs in the root of the superior vena cava, which in the chloralosanized animal produce tachycardia, bradycardia and ectopic rhythms, have apparently no effect in the unanesthetized animal with the exception of the solitary occurrence of tachycardia as part of the picture of dyspnea, tachypnea and excitement. There is, therefore, no clear evidence to indicate that the region at the root of the superior vena cava is implicated in the cardiac acceleration following increase of the venous return. The location at which the Bainbridge reflex is initiated still remains to be detd.

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