MUCOSOLVAN IN THE TREATMENT OF PATIENTS WITH PRIMARY SJÖGREN'S SYNDROME
- 1 August 1984
- journal article
- research article
- Published by Wiley in Acta Ophthalmologica
- Vol. 62 (4) , 537-541
- https://doi.org/10.1111/j.1755-3768.1984.tb03965.x
Abstract
Patients with primary Sjogern''s syndrome were randomized to mucosolvan (60 mg .times. 2 daily) or placebo, in a double-blind cross-over study. Each period of treatment was 3 wk with 1 wk wash-out in between. None of the objective ophthalmological tests (Schirmer-1-test, break-up time, van Bijsterveld score, cornea sensitivity, appearance of nuclear chromatin in conjunctival epithelial cells, tear lysozyme) improved during the investigation period.Keywords
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