THE MORPHOLOGICAL, ENDOCRINE AND TECHNICAL FACTORS CONSIDERED IN RELATION TO THE RESULT OF EMBRYO REIMPLANTATION IN HUMAN UTERUSES

  • 1 January 1983
    • journal article
    • research article
    • Vol. 12  (6) , 643-647
Abstract
Out of 161 cycles in which the procedure was attempted, 20 clinical pregnancies were obtained by in vitro fertilization and embryo transplant. The following seem to be among the numerous parameters that can affect the result favorably. At the time of oocyte recovery, large follicles (23 mm), following treatment with Clomid, gave oocytes with pregnancy. Medium B2 added to human serum gave high fertilization rates (80%) and cell division rates (75%) following in vitro culture. Only those embryos where cell division occurred quickly gave rise to pregnancies. As far as the transplant was concerned, the pregnancy rate rose from 12 to 30% according to whether one replaced 1 or 2 embryos in the uterus. Preliminary examination of the cervical canal indicated whether it should be dilated in cases where it was difficult to introduce the catheter. Giving valium made the uterus relax whereas adding blood serum (50-75%) in the transfer medium increased the viscosity of this latter. Of the 20 pregnancies, 19 resulted when the embryo transfer was easily accomplished.

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