Cold allodynia and hyperalgesia in neuropathic pain: the effect of N -methyl-d-aspartate (NMDA) receptor antagonist ketamine – a double-blind, cross-over comparison with alfentanil and placebo
- 1 February 2003
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Pain
- Vol. 101 (3) , 229-235
- https://doi.org/10.1016/s0304-3959(02)00122-7
Abstract
Cold allodynia and hyperalgesia are frequent clinical findings in patients with neuropathic pain. While there have been several clinical studies showing the involvement of central sensitization mechanisms and N-methyl-d-aspartate (NMDA) receptor activation in mechanical allodynia/hyperalgesiKeywords
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