EFFECT OF ULTRAVIOLET AND GAMMA-RADIATIONS ON HERPETOMONAS-SAMUELPESSOAI

  • 1 January 1979
    • journal article
    • research article
    • Vol. 36  (3) , 257-266
Abstract
The influence of UV and .gamma.-radiations on H. samuelpessoai grown either in a chemically defined or in a complex medium was studied. Cells cultivated in defined medium were inhibited more by UV than those from complex medium. The effect of .gamma.-radiation was independent of the cell growth media. Both radiations interfered with the plasma membrane as analyzed by parameters such as excretion of cellular material and concanavalin-A-induced agglutination. Doses of UV which inhibit the cellular growth do not interfere with the plasma membrane. With .gamma.-radiation, doses which inhibit cellular growth also interfere with the plasma membrane. For certain applications UV radiation may be an advantage in vaccine production.