Randomized Trial of High Loading Dose of Clopidogrel for Reduction of Periprocedural Myocardial Infarction in Patients Undergoing Coronary Intervention
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- 26 April 2005
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 111 (16) , 2099-2106
- https://doi.org/10.1161/01.cir.0000161383.06692.d4
Abstract
Background— Aggressive platelet inhibition is crucial to reduce myocardial injury and early cardiac events after coronary intervention. Although observational data have suggested that pretreatment with a high loading dose of clopidogrel may be more effective than a conventional dose, this hypothesis has never been tested in a randomized trial.Keywords
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