Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements

1 February 1984

journal article
research article
Published by Springer Nature in Nature

Vol. 307 (5953) , 708-714
https://doi.org/10.1038/307708a0

Abstract

Two simian virus 40 transcriptional promoter elements, the 72-base pair (bp) repeat and the 21-bp repeat region, induce chromatin structures of increased DNase I sensitivity when transposed elsewhere in the viral genome. The induction of a sufficiently long stretch of DNase I-sensitive chromatin leads to the appearance of a visible nucleosome-free region.

Keywords

This publication has 43 references indexed in Scilit:

Simian virus 40 early- and late-region promoter functions are enhanced by the 72-base-pair repeat inserted at distant locations and inverted orientations.
Molecular and Cellular Biology, 1983
Structure and Function of the Promoter-Enhancer Region of Polyoma and SV40
Cold Spring Harbor Symposia on Quantitative Biology, 1983
Deletion mutants which affect the nuclease-sensitive site in simian virus 40 chromatin.
Molecular and Cellular Biology, 1982
Formation of a nucleosome-free region in SV40 minichromosomes is dependent upon a restricted segment of DNA
Virology, 1982
Deoxyribonuclease II as a probe to sequence-specific chromatin organization: preferential cleavage in the 72 bp modulator sequence of SV40 minichromosome
Nucleic Acids Research, 1982
Territorial limits and functional anatomy of the simian virus 40 replication origin.
Proceedings of the National Academy of Sciences, 1982
The appearance of DNase I hypersensitive sites at the 5′ end of the late SV40 genes is correlated with the transcriptional switch
Nucleic Acids Research, 1981
A nucleosome-free region in SV40 minichromosomes
Nature, 1980
Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNA
Cell, 1980
Sites in simian virus 40 chromatin which are preferentially cleaved by endonucleases
Cell, 1978