Observations on Septicemia of Cattle Caused by a Haemophilus-Like Organism

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Abstract
A septicemia caused by a Haemophilus-like organism occurs singly and multiplicate in feedlot and pastured cattle and has been reproduced experimentally. Clinically the disease may be peracute and neurologic, acute and respiratory, subchronic to chronic and arthritic, or an amalgam. Grossly, lesions are widespread but most prevalent are multifocal hemorrhagic necrosis of the brain, meningitis, polyarthritis, polyserositis, and pseudomembranous or ulcerative laryngitis. Histologically, there are intense vasculitis, thrombosis, infarction, and a purulent exudate. The lesions of the experimental infection in cattle and mice resemble the natural ones.

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