MICROBIAL CONVERSION OF ANTHRACYCLINE ANTIBIOTICS I. MICROBIAL CONVERSION OF ACLACINOMYCIN BTO ACLACINOMYCIN A
- 1 January 1983
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 36 (11) , 1458-1459
- https://doi.org/10.7164/antibiotics.36.1458
Abstract
Streptomyces galilaeus OBB-111 and its blocked mutant converted aclacinomycin B, and related anthracycline glycosides of the B type to the corresponding A type glycosides. Only the cell fraction of cultures of S. galilaeus OBB-111 catalyzed the reaction. The activity was associated with growth, but dissappeared before the start of rapid production of aclacinomycins A and B.This publication has 2 references indexed in Scilit:
- New anthracycline antibiotics, auramycins and sulfurmycins. I. Isolation and characterization of auramycins A and B, and sulfurmycins A and B.The Journal of Antibiotics, 1982
- Enzymatic conversion of aclacinomycin a to Y by a specific oxidoreductase in Streptomyces.The Journal of Antibiotics, 1978