Asymmetric addition of allyltrimethylsilane to (–)-menthyl pyruvate and phenylglyoxylate

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Abstract
The reaction of allyltrimethylsilane with α-keto esters in the presence of titanium tetrachloride afforded a γδ-unsaturated α-hydroxyvalerate in high yield, which with chiral α-keto esters in asymmetric synthesis gave 16–55% enantiomeric excess product.