A Study of Cortical Oxygen Tension During Induced Hypotension

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Abstract
In recent years the initial wave of enthusiasm for the use of induced hypotension by ganglionic blockade during certain surgical operations has been supplanted by a desire for a more careful appraisal of the technique.1-3Clinical analyses of surgical patients subjected to hypotension have provided useful, but incomplete, information because of the many uncontrollable variables—in particular, the loss of blood during surgery. Although much work has been done on the various aspects of hemorrhagic hypotension or shock and the influence thereon of surgical or chemical sympathectomy, most of the interest has been directed toward visceral changes4,5and survival rates in animals kept hypotensive by the techniques of Wiggers and Fine.6-10Except for a few isolated instances,11-13the relationship between the cerebral and the systemic hemodynamics has received very little attention, and little is known about the cerebral hemodynamic responses either to hemorrhagic hypotension, per se, or

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