Variable contribution of cytochromes p450 2d6, 2c9 and 3a4 to the 4-hydroxylation of tamoxifen by human liver microsomes
- 24 January 1997
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 53 (2) , 171-178
- https://doi.org/10.1016/s0006-2952(96)00650-8
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Variable contribution of CYP2D6 to the N‐Dealkylation of S‐(‐)‐propranolol by human liver microsomesBritish Journal of Clinical Pharmacology, 1996
- Evidence That Aspartic Acid 301 Is a Critical Substrate-Contact Residue in the Active Site of Cytochrome P450 2D6Published by Elsevier ,1995
- Tamoxifen: Toxicities and Drug Resistance During the Treatment and Prevention of Breast CancerAnnual Review of Pharmacology and Toxicology, 1995
- Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9Xenobiotica, 1995
- Genotoxicity of tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450sCarcinogenesis: Integrative Cancer Research, 1994
- A Risk-Benefit Assessment of Tamoxifen TherapyDrug Safety, 1993
- Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactionsChemical Research in Toxicology, 1992
- Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspectsChemical Research in Toxicology, 1991
- Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1Chemical Research in Toxicology, 1990
- Life threatening interaction between tamoxifen and warfarin.BMJ, 1989