Effect of Interferon on Murine Cytochrome P-450: Effect of Partially Purified Antigen-Specific Interferon-Gamma
- 1 January 1983
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Interferon Research
- Vol. 3 (2) , 219-222
- https://doi.org/10.1089/jir.1983.3.219
Abstract
Gamma interferon (IFN-γ), induced by sensitization of mice with Mycobacterium bovis strain BCG followed by challenge with tuberculin, was partially purified by adsorption on silicic acid. Administration of the partially purified IFN-γ to mice significantly depressed levels of liver microsomal cytochrome P-450 to an equivalent extent as crude IFN-γKeywords
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