Treatment of Infestation with Phthirus pubis

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Abstract
There has been a steady increase in the incidence of infestation with P. pubis, a sexually transmitted louse. A recently introduced non-prescription liquid pediculicide, whose major ingredient is 0.3% pyrethrins synergized by 3.0% piperonyl butoxide (RiD), was compared for efficacy and safety with a prescription-only pediculicidal lotion whose major ingredient is 1% .gamma.-BHC (Kwell). Adult men and women (30) with P. pubis infestation were assigned randomly to treatment with the synergized pyrethrins or .gamma.-BHC. A single 10 min application of the synergized-pyrethrin liquid produced the same results as a single 12 h application of the .gamma.-BHC lotion: total eradication of adult lice and nymphs, cessation of pruritus and no treatment-induced side effect. A follow-up visit 1 wk after treatment verified all eradications.

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