Pertussis Vaccination and Asthma: Is There a Link?

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Abstract
To the Editor. —From the article by Drs Ellis and Douglas,1it appears that where the overall population of infants is concerned, the use of acellular pertussis vaccine might be one of the main changes to be expected in the near future. This gives us an opportunity to report unexpected findings apparently linked with the use of the current inactivated bacterial vaccine. We were studying criteria of health in 448 children and adolescents. All of them received only breast milk during the first 6 months, and in particular on the first day following birth. All of them were weaned after 1 year of age and were older than 4 years at the time the parents responded. The mean age was 7.87 years. To the question "Has your child ever been diagnosed as asthmatic?" there were 30 positive answers (6.72%). The surprise came when we classified the questionnaire according to

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