Red Cell ABH Antigens in Leukaemias and Lymphomas

Abstract
The qualitative and quantitative determinations of A, B and H antigens were studied in blood samples of 509 normal subjects and 114 patients. Eleven of 53 (20.75%), 3 of 27 (11.11%) and 4 of 34 (11.76%) of adults with leukemia, children with leukemia and adults with lymphomas, respectively, show significantly lower antigenic scores than normal controls. Since all A, B and H antigens were independently affected, the destruction of well-developed ABH antigens by a certain substance produced during the course of the disease was suspected.