The Response of Chickens to Vaccination with Different Concentrations of Pigeon Pox and Fowl Pox Viruses
- 1 May 1965
- journal article
- research article
- Published by JSTOR in Avian Diseases
- Vol. 9 (2) , 237-+
- https://doi.org/10.2307/1588007
Abstract
Pigeon pox and fowl pox vaccine viruses were administered by the wing web route to chickens in different concentrations. When the vaccine titer was approximately 104 embryo infective doses50 (EID50) per ml, a take reaction from vaccination was present in only 20 and 60% of the vaccinated chickens in the 2 respective trials. Nevertheless, the immune proportion, at least on a short-term basis, was 100 and 90%. Above this virus concentration, however, both takes and resistance to the challenge virus proved satisfactory. Below a 104 titer, takes and immunity were both poor. No differences were apparent in infective dose requirements between the two viruses. This study suggests that pigeon and fowl pox vaccines with the virus strains tested should possess minimum virus concentrations of 105 EID50 per ml to establish satisfactory takes in parallel with good immunity.This publication has 0 references indexed in Scilit: