Phosphatidic acids and derivatives. IX. A new synthesis of glycolkephalins and glycerol‐α‐kephalins
- 1 January 1960
- journal article
- research article
- Published by Wiley in Recueil des Travaux Chimiques des Pays-Bas
- Vol. 79 (4) , 330-341
- https://doi.org/10.1002/recl.19600790402
Abstract
A new synthesis of glycerol‐α‐kephalins and glycolkephalins is described. The corresponding silver benzyl diacylglycerol‐α‐phosphate or silver benzyl glycolphosphate is boiled in benzene solution with 2‐(dibenzylamino)ethyl bromide, and the O,N,N‐tribenzyl derivative of the kephalin thus obtained is converted into the kephalin by hydrogenolysis. The overall yields are 80‐90 %.Keywords
This publication has 14 references indexed in Scilit:
- Synthesis of L-α-(Dioleoyl)-cephalin; with a Comment on the Stereochemical Designation of Glycerolphosphatides1Journal of the American Chemical Society, 1959
- 603. The synthesis of cephalin (phosphatidylethanolamine) and batyl, chimyl, glycol, and alkyl analoguesJournal of the Chemical Society, 1958
- Phosphatide acids and derivatives. VII. The use of silver phenyl benzyl phosphate for the synthesis of monophenyl esters of phosphatidic acidsRecueil des Travaux Chimiques des Pays-Bas, 1958
- Zur Synthese der Phosphatide. Eine neue Synthese der KephalineHelvetica Chimica Acta, 1957
- Dealkylation and Debenzylation of Triesters of Phosphoric Acid. Phosphorylation of Hydroxy and Amino CompoundsJournal of the American Chemical Society, 1955
- Phosphatidic acids and derivatives: IV). Synthesis of α‐glycerophosphatidic acids, starting from glycerol‐α‐iodohydrinRecueil des Travaux Chimiques des Pays-Bas, 1954
- Synthesis of Enantiomeric α-Cephalins1,2Journal of the American Chemical Society, 1952
- Adrenergic Blocking Agents. I. N-(2-Chloroethyl)-dibenzylamine SeriesJournal of the American Chemical Society, 1950
- Dimyristo- and Eruco-stearo-cephalinJournal of the American Chemical Society, 1948
- Synthesis of Cephalin1Journal of the American Chemical Society, 1947