Prenatal detection of cri du chat syndrome on uncultured amniocytes using fluorescence in situ hybridization (FISH)

1 January 1994

journal article
case report
Published by Wiley in Clinical Genetics

Vol. 45 (1) , 17-20
https://doi.org/10.1111/j.1399-0004.1994.tb03983.x

Abstract

Fluorescence in situ hybridization (FISH) with a chromosome-region-specific DNA probe was used prospectively on uncultured amniocyte interphase cells to detect an unbalanced chromosome abnormality that resulted in cri du chat or 5p- syndrome. Confirmation was performed by routine cytogenetics.

Keywords

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