Bioisosterism: A Useful Strategy for Molecular Modification and Drug Design
Top Cited Papers
- 1 January 2005
- journal article
- review article
- Published by Bentham Science Publishers Ltd. in Current Medicinal Chemistry
- Vol. 12 (1) , 23-49
- https://doi.org/10.2174/0929867053363540
Abstract
This review aim to demonstrate the role of bioisosterism in rational drug design as well as in the molecular modification and optimization process aiming to improve pharmacodynamic and pharmacokinetic properties of lead compounds.Keywords
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