Facile synthesis of basic skeletons of naturally occurring lactonic terpenes
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 5,p. 1383-1385
- https://doi.org/10.1039/p19810001383
Abstract
Simple syntheses of the basic skeletons of some naturally occurring terpenes possessing lactone moieties are described. Thermolysis of 1,2-dihydro-6-methoxybenzocyclobuten-1-yl but-3-enoate (4) in a sealed tube at 180–200 °C afforded the cyclised lactone (5) in moderate yield. On similar treatment, the benzocyclobutenes (11) and (14) gave the corresponding fused lactones (12) and (15) respectively.This publication has 1 reference indexed in Scilit:
- Studies on the syntheses of heterocyclic compounds. 675. A facile regiospecific and stereocontrolled synthesis of a diterpene alkaloid intermediate from benzocyclobutenesJournal of the American Chemical Society, 1976