Melatonin Inhibits Prostaglandin E Release From the Medial Basal Hypothalamus of Pinealectomized Rats
- 1 October 1984
- journal article
- research article
- Published by Wiley in Journal of Pineal Research
- Vol. 1 (4) , 317-321
- https://doi.org/10.1111/j.1600-079x.1984.tb00222.x
Abstract
The effects of pinealectomy and of melatonin administration on prostaglandin E synthesis in the medial basal hypothalamus were studied in male rats. Melatonin treatment significantly decreased prostaglandin E release from the medial basal hypothalamus in pinealectomized rats. Apparently, melatonin modulates hypothalamo-hypophyseal function, at least in part, via inhibition of hypothalamic prostaglandin synthesis.Keywords
This publication has 11 references indexed in Scilit:
- Release of E Prostaglandins into the Cerebrospinal Fluid and Its Inhibition by Melatonin after Cervical Stimulation in the Rabbit*Endocrinology, 1982
- A comparison of the inhibitory effects of melatonin and indomethacin on platelet aggregation and thromboxane releaseProstaglandins, 1980
- Melatonin blocks in vitro generation of prostaglandin by the uterus and hypothalamusEuropean Journal of Pharmacology, 1980
- Developmental Loss of the Acute Inhibitory Effect of Melatonin on thein VitroPituitary Luteinizing Hormone and Follicle-Stimulating Hormone Responses to Luteinizing Hormone-Releasing Hormone*Endocrinology, 1979
- A new technique of pinealectomy for adult ratsCellular and Molecular Life Sciences, 1977
- Effect of Inhibitors of Prostaglandin Synthesis on Gonadotropin Release in the Rat1Endocrinology, 1975
- Prostaglandin E2-Induced Release of LHRH into Hypophysial Portal Blood1Endocrinology, 1975
- Prostaglandin E2-Induced Release of Luteinizing Hormone-Releasing Factor (LRF)Neuroendocrinology, 1975
- Effects of Melatonin on Changes Induced by Castration and Testosterone in Sexual Structures of Male RatsEndocrinology, 1970
- MITOTIC ACTIVITY IN THE ADENOHYPOPHYSIS OF RATS AFTER PINEALECTOMYJournal of Endocrinology, 1968