HISTOPATHOLOGIC AND ELECTRON-MICROSCOPIC STUDIES OF CUTANEOUS LESIONS IN CALVES WITH EXPERIMENTALLY INDUCED EAST COAST FEVER (THEILERIOSIS)

Google Scholar
  • 1 January 1978
    • journal article
    • research article
    • Vol. 39  (7) , 1117-1122
Abstract
Skin lesions of bovine East Coast fever were examined by light microscopy and EM 120 h after attachment of Rhipicephalus appendiculatus ticks infected with Theileria parva. Lesions included epidermal ulcer, hemorrhage, edema, necrosis and inflammatory cell infiltration by mostly polymorphonuclear and mononuclear (lymphoid) cells. The trophozoite stage of T. parva was observed in a parasitophorous vacuole and feeding on neutrophil granules. Schizonts, some in budding process, and merozoites were extracellular and among many mononuclear phagocytes (lymphoid cells). Some merozoites were in mononuclear phagocytes and a granulocyte. Some of the cells had already transformed into lymphoblasts with pseudopodia.