Conformational analysis of N-[3,4-dihydro-4-oxoquinazolin-3-yl]aziridines

Abstract
The X-ray crystal structure of the aziridine (7a) shows that the preferred orientation around the N–N bond has the lone pairs of electrons on adjacent nitrogens eclipsed; the rotamer equilibria around the N–N bonds in the two stereoisomers (7a) and (7b) suggest that this is also the preferred conformation for these substituted hydrazines in solution.

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