Neuroleptic reduction of cocaine-induced paranoia but not euphoria?
- 1 August 1986
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 90 (1) , 142-143
- https://doi.org/10.1007/bf00172886
Abstract
Central dopaminergic activation is hypothesized to underly schizophrenia and, paradoxically, stimulant euphoria. Four cocaine abusers with histories of stimulant-induced paranoid psychoses reported selective reduction in psychotic symptoms but not euphoria when treated with dopamine blockers. This provides preliminary evidence against efficacy of neuroleptics in cocaine abuse prevention, and suggests euphoria and paranoia may have discriminable neurophysiological substrates.This publication has 6 references indexed in Scilit:
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