GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

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Open Access

3 February 2009

journal article
research article
Published by Springer Nature in BMC Bioinformatics

Vol. 10 (1) , 48
https://doi.org/10.1186/1471-2105-10-48

Abstract

Since the inception of the GO annotation project, a variety of tools have been developed that support exploring and searching the GO database. In particular, a variety of tools that perform GO enrichment analysis are currently available. Most of these tools require as input a target set of genes and a background set and seek enrichment in the target set compared to the background set. A few tools also exist that support analyzing ranked lists. The latter typically rely on simulations or on union-bound correction for assigning statistical significance to the results.

Keywords

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