Quantitative Investigation of Sudanophilic Lesions around the Aortic Ostia of Human Fetuses, Newborn and Children

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Abstract
The sudanophilic lesions around the aortic ostia of 10 fetuses, 10 newborns and 10 children aged up to 1 year were studied using a polar coordinate mapping method. The periorificial sudanophilic lesions develop initially distal to the orifices and show a continuous increase with age in percentage and extent. In children the lesions nearly completely surround all the ostia with a significant distal peak. There was no sex difference; the involvement of the right and left side was comparable. The comparison of the morphological data from the parents and children with anamnestics showed no relationship.