Towards a behavioral typology of Alzheimer's patients
- 30 September 1986
- journal article
- research article
- Published by Taylor & Francis in Journal of Clinical and Experimental Neuropsychology
- Vol. 8 (5) , 594-610
- https://doi.org/10.1080/01688638608405178
Abstract
Neuropsychological test performance and estimates of regional rates of cortical glucose metabolism obtained via positron emission tomography are presented for patients with Alzheimer''s disease (AD). Analyses of these data indicated the presence of distinct subgroups characterized by qualitatively different profiles of cognitive impairment and corresponding patterns of cerebral hypometabolism. No subgroup differences were noted with regard to age at onset or reported duration of symptom. These findings indicate that, in a given individual, AD may initially invade a relatively circumscribed cortical region. Thus, although AD may constitute a singl disease process, it does not result in a unitary neuropsychological syndrome.This publication has 48 references indexed in Scilit:
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