T‐cell survival and the role of cytokines
- 1 June 2001
- journal article
- review article
- Published by Wiley in Immunology & Cell Biology
- Vol. 79 (3) , 199-206
- https://doi.org/10.1046/j.1440-1711.2001.00999.x
Abstract
Typical T cells are long-lived resting cells. Despite their quiescent appearance, there is increasing evidence that T cells are subjected to continuous stimulation through contact with various stimuli, notably by self peptide/MHC complexes and cytokines. These stimuli keep T cells alive and also cause intermittent entry into cell cycle.Keywords
Funding Information
- U.S. Public Health Service (CA38355, CA25803, AI21487, AI32068, AG01743)
- Scripps Research Institute (13753‐IMM)
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