Electron Capture Gas Chromatographic Assay for Miconazole and Clotrimazole In Skin Samples
- 1 January 1978
- journal article
- pharmaceutical
- Published by Taylor & Francis in Analytical Letters
- Vol. 11 (6) , 461-468
- https://doi.org/10.1080/00032717808067887
Abstract
Electron capture gas chromatographic assay procedures were developed for quantitating the antifungal agents clotrimazole and miconazole. The procedures were specifically developed for analysis of the drugs in superficial samples of human skin. The analytical methods were sensitive to 5 ng of miconazole and 10 ng clotrimazole per tissue sample.Keywords
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