Impact of Fat and Glucose Administration on Metabolic and Respiratory Interactions in Sepsis
- 1 March 1989
- journal article
- research article
- Published by Wiley in Journal of Parenteral and Enteral Nutrition
- Vol. 13 (2) , 141-146
- https://doi.org/10.1177/0148607189013002141
Abstract
Metabolic and respiratory interactions were analyzed in a large group of septic patients (S) and in a reference group of nonseptics (NS) during the iv administration of glucose and fat. In spite of a moderate increase in CO2 production (VCO2) observed during the administration of fat in S, a VCO2-sparing effect of fat, with respect to equicaloric amounts of glucose, was reconfirmed. The relevance of the therapeutic modulation of CO2 production during parenteral nutrition, and the relative impact on the abnormal septic respiratory patterns, were emphasized by analyzing the physiological relationships and mechanisms responsible for the increase in respiratory work in sepsis. (Journal of Parenteral and Enteral Nutrition 13:141-146, 1989)This publication has 18 references indexed in Scilit:
- Increased Lipid Fuel Dependence in the Critically 111 Septic PatientPublished by Wolters Kluwer Health ,1984
- Respiratory Quotient and Patterns of Substrate Utilization in Human Sepsis and TraumaJournal of Parenteral and Enteral Nutrition, 1983
- Relations Between Circulatory and Metabolic Changes in SepsisAnnual Review of Medicine, 1981
- Lipid infusion in critically ill patientsCritical Care Medicine, 1981
- Influence of Total Parenteral Nutrition on Fuel Utilization in Injury and SepsisAnnals of Surgery, 1980
- Effects of Hypercaloric Glucose Infusion on Lipid Metabolism in Injury and SepsisPublished by Wolters Kluwer Health ,1979
- VentilationPublished by Wolters Kluwer Health ,1979
- Intravenous fat therapy—II. Changes in oxygen consumption and respiratory quotientBritish Journal of Surgery, 1967
- Prediction of lean body mass from height and weightJournal of Clinical Pathology, 1966
- PULMONARY INSUFFICIENCYMedicine, 1948