Elevated Serum Neopterin Levels in Acute Rheumatic Fever
Open Access
- 1 February 1993
- journal article
- Published by Walter de Gruyter GmbH in Pteridines
- Vol. 4 (1) , 39-42
- https://doi.org/10.1515/pteridines.1993.4.1.39
Abstract
Summary A link between acute rheumatic fever (ARF) and autoimmune disorders has been postulated. To investigate this relationship. we performed radioimmunoassay measurements of serum neoplerin levels in patients with ARF. Twenty-five young men with ARF were included in our study. Patients were investigated on 3-7 days after the onset of symptoms and on the 30th-35th days after onset. Serum neopterin levels were elevated (>8.7 nmol/L) in 17 out of 25 patients with ARF. Mean neopterin concentration was significantly higher in ARF patients (10.9± 3.9 nmol/L) compared to healthy controls (5.2± 2.1 nmol/L; pKeywords
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