Dendritic cell subsets in primary and secondary T cell responses at body surfaces
Top Cited Papers
- 16 November 2009
- journal article
- review article
- Published by Springer Nature in Nature Immunology
- Vol. 10 (12) , 1237-1244
- https://doi.org/10.1038/ni.1822
Abstract
We examine the role of dendritic cells subsets in immunity to peripheral infections, with emphasis on the differences in the regulation of primary and secondary T cell responses to viruses. Our major focus is on new developments in the understanding of immunity to infections of the skin and lung, which are crucial entry points for a variety of infectious pathogens. Initially we describe a diverse network of dendritic cell subsets, but then we argue for a more generalized model of reduced complexity.Keywords
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