Modeling Interactome: Scale-Free or Geometric?

Preprint

17 April 2004

preprint
Published by arXiv in arXiv

https://doi.org/10.48550/arXiv.q-bio/0404017

Abstract

Networks have been used to model many real-world phenomena to better understand the phenomena and to guide experiments in order to predict their behavior. Since incorrect models lead to incorrect predictions, it is vital to have a correct model. As a result, new techniques and models for analyzing and modeling real-world networks have recently been introduced. One example of large and complex networks involves protein-protein interaction (PPI) networks. We demonstrate that the currently popular scale-free model of PPI networks fails to fit the data in several respects. We show that a random geometric model provides a much more accurate model of the PPI data.

Keywords

MODELING INTERACTOME
PROTEIN INTERACTION
GEOMETRIC MODEL
WORLD PHENOMENA
NEW TECHNIQUES
MODELING REAL
SCALE FREE
INCORRECT
PPI

All Related Versions

Version 1, 2004-04-17, ArXiv

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