ON ENZYME-SUBSTRATE RELATIONSHIPS DURING BIOCHEMICAL DIFFERENTIATION
- 1 June 1960
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 46 (6) , 798-803
- https://doi.org/10.1073/pnas.46.6.798
Abstract
Isocitric dehydrogenase, glucose-6-phosphate dehydrogenase, glutamic dehydrogenase, and glutamic-pyruvic trans -aminase do not change in concentration during differentiation in Dictyostelium discoideum, in spite of alterations in the intensity of metabolic pathways probably involving changing activities of these enzymes in vivo. It is suggested that sequential substrate utilization (and inhibition) could account for some metabolic changes occurring during differentiation.This publication has 10 references indexed in Scilit:
- AN ARGINASE INHIBITOR(S) AND ITS POSSIBLE ROLE IN THE DEVELOPMENTAL DECREASE OF ARGINASE ACTIVITY IN CHICK EMBRYOSThe Biological Bulletin, 1959
- Biochemical differentiation in the slime moldBiochimica et Biophysica Acta, 1959
- The histochemical localization of certain biochemical intermediates and enzymes in the developing slime mold, Dictyostelium discoideum RaperJournal of Experimental Zoology, 1958
- Alkaline phosphatase activity in the developing slime mold, Dictyostelium discoideum raperJournal of Experimental Zoology, 1956
- Biochemical events accompanying stalk formation in the slime mold, Dictyostelium discoideumJournal of Cellular and Comparative Physiology, 1956
- The oxidative activity of particulate fractions from germinating castor beansBiochemical Journal, 1956
- A histochemical study of differentiation in the cellular slime moldsJournal of Experimental Zoology, 1955
- NITROGEN METABOLISM OF THE SLIME MOLD DICTYOSTELIUM DISCOIDEUM DURING GROWTH AND MORPHOGENESISThe Biological Bulletin, 1954
- Oxygen utilization in relation to growth and morphogenesis of the slime mold Dictyostelium discoideumJournal of Experimental Zoology, 1950
- PURIFICATION OF THE HYPERGLYCEMIC-GLYCOGENOLYTIC FACTOR FROM INSULIN AND FROM GASTRIC MUCOSAJournal of Biological Chemistry, 1949